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Users are taken step-by-step through the process to create a circular comparison image via a graphical user interface (Figure 2). In the first screen (Figure 2A), users specify data they would like to compare to a central reference sequence. In the second screen (Figure 2B), users are able to configure the individual concentric rings; choosing which data they would like to show in each lane and make aesthetic choices including colour or ring size. Lastly, the settings can be reviewed and submitted for BLAST [19] alignment and image drawing using CGView [16] (Figure 2C). Image rendering settings and genome comparison configurations for a particular BRIG image can be saved and reused as an XML profile file. Alternatively, a number of sample templates are available to users, in order to quickly generate an image with optimised size and colour settings.




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BRIG is actively maintained with a manual that includes step-by-step tutorials and sample data providing walk-throughs of all the major features. In future we plan to develop support for genome comparisons generated by programs like MUMmer [23] and for BRIG to calculate the co-ordinates of major regions of difference between genomes 'on-the-fly' for use in downstream analyses.


In-app purchase keys are private and can only be downloaded once. After downloading the key, store it in a safe place. Remember to revoke a key immediately if it becomes lost or compromised and ensure that offers using this key are updated.


If your app distributes Wallet passes that require ongoing updates from your app or web service, the passes will eventually need to be reissued using a new identifier after transfer is complete so they can be signed with certificates issued from your Apple Developer account. To minimize user confusion and avoid interruption, we recommend providing a message in your app to let users know that their previously issued pass will become inactive and to download a new pass from your app or web service.


The device type is the target device for the variant. Universal refers to the variant that runs on all supported operating systems and target devices that are delivered to customers running iOS 8 and earlier, apps purchased in volume through Apple School Manager and Apple Business Manager or through Mobile Device Management (MDM), or apps downloaded using iTunes 12.6 or earlier.


If any of the device variant sizes exceed the 200 MB over-the-air download limit, a yellow warning appears next to the build string in the Builds table and next to the variant size in the App Store File Sizes table. Click the warning icon to read the full warning. Apple will also send you an email with this information.


Testers install the free TestFlight app on their devices. Then they use their invitation email or a public link to accept invitations, install your app, send feedback, and get updates. Testers download and install thinned variants of your app.


If you have builds available for testing, the users you selected will receive an email inviting them to test the app. The users will be directed to accept the invitation using the TestFlight app on their device or via a redemption code. Internal testers will be able to download and test all builds for 90 days.


Before releasing your app on the App Store for the first time, you can choose to offer it for pre-order. Customers can view your product page and order your app before it's released for download. Once your app is released, customers are notified and your app automatically download on the device on which they made the pre-order. It will also download on their other devices if they turned on automatic downloads . For paid apps, customers are charged before download.


While your app is available for pre-order, you can update your app by creating and submitting a new version. The new version must be approved before it can be published for pre-order on the App Store, so be sure to follow the App Review Guidelines. If you submit a version update during the pre-order period, customers will receive the latest version published to the App Store once your app is released for download.


Once your app is approved and you're ready to make it available for pre-order, return to Pricing and Availability. Confirm the date your app will be released for download, and click Release as Pre-Order on the top right.


Your app will be released to the App Store. Customers who pre-ordered your app will be notified and your app will automatically download to their device. For paid apps, customers will be charged before download.


Public: Your app will be publicly available on the App Store in the territories you selected and available to anyone for volume purchase through Apple Business Manager or Apple School Manager.


All apps listed on the App Store are automatically available for volume purchase for the same price in Apple Business Manager and Apple School Manager, which is where businesses and educational institutions download apps for volume distribution.


You can specify one or more organizations that can view and download the app in Apple Business Manager or Apple School Manager. They can then distribute it through Mobile Device Management or redemption codes.


Under Type, choose either Organization ID or Apple ID, and enter the required information. Enter the Organization ID to make the app visible in the organization's Apple Business Manager or Apple School Manager account. For businesses still using the legacy Volume Purchase Program, you can assign an app to their volume purchasing Apple ID.


Payments and Financial Reports provides information on final payments made to you based on settled transactions and finalized proceeds using the Apple fiscal calendar. Financial reports only include paid transactions for which payment was collected from the customer (review the Paid Applications Agreement for details). You can opt in to email alerts that notify you when financial reports are available for download in App Store Connect.


Exchange rate. Sales and Trends estimates the USD amount of sales and proceeds based on a rolling average of the previous month's exchange rates. All downloadable reports show amounts in local currencies transacted by customers. Final payments in Payments and Financial Reports are based on the exchange rate used to convert each report currency to the currency of your bank account. Learn about the exchange rate.


Click an event name in the list to display an overview page of key metrics about your in-app event. An overview of your event's performance includes how many times your event was viewed, the total number of app downloads from your event, retention, and more.


When a user taps a link from an app, website, or App Clip card that brings them to your App Store product page, the immediate product page view is attributed to the referring app, website, or App Clip. If the user then taps to download the app for the first time, the resulting First-Time Download is attributed to the referring app, website, or App Clip.


All sales and usage data for the app or App Clip are attributed to the source recorded when a user tapped to download your app or launch your App Clip for the first time. This includes data from redownloads, downloads to multiple devices sharing the same Apple ID, subscription renewals, and Family Sharing downloads.


Sales and usage data display sources as unavailable if users downloaded your app before App Analytics started tracking source attribution on April 15, 2017. As users download your app for the first time, more complete sources data will display. If a user downloads your app using an App Store gift card or promotional code, the source type will also show as unavailable.


For example, if your app was first downloaded by customers on 100 devices on May 1, and seven days later on May 8, 20 devices are still active with at least one session, the retention rate on May 8 is 20% (or 20 active devices out of 100).


By default, data is shown in Coordinated Universal Time (UTC). To match the time zone used by downloaded reports, select Pacific Time (PT). A day includes transactions that happened from 12:00 a.m. to 11:59 p.m. for the selected time zone.


The number of first-time purchases of your app or bundle. An app unit or bundle unit is counted when a customer taps the 'Buy' or 'Get' button for the first-time. App updates, downloads from the same Apple ID onto other devices, and redownloads to the same device aren't counted. Family Sharing downloads are included for free apps, but not for paid apps.


Before releasing your app on the App Store for the first time, you can choose to offer it as a pre-order. Making your app available for pre-order allows customers to order it before its release date and automatically download it once it's available. Upon fulfillment to the customer, a pre-order will be reflected as an app unit. If a pre-order is a paid app unit, then the associated sales from the pre-order will also appear upon fulfillment.


To download a copy of the Free Apps Agreement, also referred to as the Apple Developer Program License Agreement, visit the Membership section of your developer account and click Show Agreements. Alternatively, you can view Apple Developer Program agreements on the developer website.


To make updates to your U.S. tax information, contact us. Alternatively, you can download, complete, and sign your applicable tax form from the Internal Revenue Service website, and send it to Apple by email or mail.


Your certification will complete Part 4 of the Quebec Form FP-2506-V, or part D of GST/HST Form 506. Apple will complete Part 5 or Part E respectively, and make the form available for you to download for your records.


If you sell content on the App Store in Brazil, an annual withholding tax certificate can be downloaded in App Store Connect. If there are multiple vendor numbers associated with your account, you'll receive a withholding certificate for each vendor number.


Monthly tax certificates and invoices for your sales on the App Store in Mexico, including Mexico VAT on Commission Invoice, Mexico Withholding IT Certificate, and Mexico Withholding VAT Certificate, are available for download in Payments and Financial Reports. 2ff7e9595c


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